The 2021 Mercedes-Benz E350 has updated looks - inside and out. Is this still the class-leading luxury sedan? We have a closer look, right now.

The Mercedes E-Class is the luxury sedan by which all other luxury sedans are measured. Available in a wide array of body styles and powertrains, the model we're looking at today is the popular sedan with optional 4Matic All Wheel Drive. It does have a few extra options, including the Driving Assistance Package, Panarama sunroof, Extra Sound deadening and more, for a total price of $64,800* US-Dollars including destination and delivery -- as you see it here.

The E350 comes standard with a 2-liter inline four-cylinder engine that's been turbo-charged for up to 255 horsepower. It's connected to a 9-speed automatic transmission with paddle shifters. Power is distributed to all four wheels through 4Matic all-wheel drive. 4Matic will intelligently manage power, both back to front and side to side, optimizing grip on any surface.

EPA rates economy at up to 30 miles to the gallon on the highway and 22 around town**.

A wide assortment of other powertrains are available, including rear-wheel drive, hybrid and a stunning AMG edition, with a whopping 429-horsepower and 384 lbs-ft of torque. Making the E-class appeal to a wide-range of buyers.

Exterior view of the Mercedes-Benz E350

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On the E350 Sedan we're testing, there was plenty of room in the truck for several golf bags. The second row also provides a class-leading experience. With lots of leg and head-room, even for an adult passenger.

Up front, the redesigned interior improves on an already stunning layout. Even standard trims offer fine-grain wood trim, with copious amounts of luxurious leather (wheel) and synthetic materials (seats). The trademark dual-display screen setup is standard on the E-class with a configurable gauge display in front of the driver, and a seamless transition to infotainment on the right. Here you can use natural voice commands to control navigation, stereo and climate controls.

User controls go deep, with full control over the cabin lighting color, safety settings, dynamic modes and a lot more. Save your settings with configurable themes. This is a fast and easy way to control the hundreds of options at your fingertips.

A class-leading sedan needs to have innovative safety. With the addition of some key option packages, you get a huge array of advanced features including: navigation-enhanced adaptive cruise control, augmented-reality-enabled navigation, collision mitigation, lane-detection, pedestrian detection, blind spot warning and a lot more.

Driving the E350 - especially when equipped with the optional Acoustic Comfort Package - is an experience like none other. This is one of the quietists and more comfortable sedans you can buy today. But it's not just smooth, it's also supremely capable, with the optional 4Matic all-wheel drive giving complete control to the drive in a variety of weather conditions.

If you're considering trading in an older Mercedes, or you're looking to move into your first luxury sedan, the E350 continues to define the category as one of the most respected sedan's on the road.

We have more than 70,000 new and used vehicles available from coast-to-coast. Find the perfect vehicle, pick your options, and arrange for a test drive at your local Autonation-affiliated Mercedes-Benz dealer.

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AutoNation Drive | May 07, 2021


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*MSRP excludes tax, license, registration, destination charge and options. Dealer prices may vary.

**Based on EPA mileage ratings. Your mileage will vary depending on specific vehicle trim, how you drive and maintain your vehicle, driving conditions, and other factors.